What is Pre-implantation genetic screening?
Pre-implantation genetic screening (PGS) is the process of checking the embryos for chromosomal abnormalities. Those abnormalities are often a factor which makes the embryo fail the implantation and cause miscarriage. They are also the cause of Down’s syndrome.
The process of PGS usually involves these steps:
- First you undergo a normal IVF or ICSI procedure where the eggs are collected and fertilized.
- For 2 to 3 days the embryo matures in the laboratory until it consists of about 8 cells.
- 1 or 2 cells are removed then from the embryo by an embryologist.
- Examination of the amount of chromosomes and their state.
- 1 to 3 embryos with normal chromosome amounts are then transferred into the womb where they develop.
- Embryos which had chromosomes with abnormalities are either discarded or left for research.
For who is PGS recommended?
PGS may be recommended to you if you are older than 35 years and there is a risk of having a baby with chromosomal abnormalities and if you had miscarriages in the past. You should consider PGS if your family has a history of chromosomal problems.